Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.

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Autores principales:	Pablo Carravilla, Jakub Chojnacki, Edurne Rujas, Sara Insausti, Eneko Largo, Dominic Waithe, Beatriz Apellaniz, Taylor Sicard, Jean-Philippe Julien, Christian Eggeling, José L. Nieva
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/32282e6593b04122a0dc319b89d08e3e
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spelling	oai:doaj.org-article:32282e6593b04122a0dc319b89d08e3e2021-12-02T14:39:16ZMolecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions10.1038/s41467-018-07962-92041-1723https://doaj.org/article/32282e6593b04122a0dc319b89d08e3e2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07962-9https://doaj.org/toc/2041-1723The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.Pablo CarravillaJakub ChojnackiEdurne RujasSara InsaustiEneko LargoDominic WaitheBeatriz ApellanizTaylor SicardJean-Philippe JulienChristian EggelingJosé L. NievaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pablo Carravilla Jakub Chojnacki Edurne Rujas Sara Insausti Eneko Largo Dominic Waithe Beatriz Apellaniz Taylor Sicard Jean-Philippe Julien Christian Eggeling José L. Nieva Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
description	The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.
format	article
author	Pablo Carravilla Jakub Chojnacki Edurne Rujas Sara Insausti Eneko Largo Dominic Waithe Beatriz Apellaniz Taylor Sicard Jean-Philippe Julien Christian Eggeling José L. Nieva
author_facet	Pablo Carravilla Jakub Chojnacki Edurne Rujas Sara Insausti Eneko Largo Dominic Waithe Beatriz Apellaniz Taylor Sicard Jean-Philippe Julien Christian Eggeling José L. Nieva
author_sort	Pablo Carravilla
title	Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
title_short	Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
title_full	Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
title_fullStr	Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
title_full_unstemmed	Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
title_sort	molecular recognition of the native hiv-1 mper revealed by sted microscopy of single virions
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/32282e6593b04122a0dc319b89d08e3e
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Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

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