Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions

The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.

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Detalles Bibliográficos
Autores principales: Pablo Carravilla, Jakub Chojnacki, Edurne Rujas, Sara Insausti, Eneko Largo, Dominic Waithe, Beatriz Apellaniz, Taylor Sicard, Jean-Philippe Julien, Christian Eggeling, José L. Nieva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/32282e6593b04122a0dc319b89d08e3e
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