Spontaneous formation of structurally diverse membrane channel architectures from a single antimicrobial peptide

Antimicrobial peptides (AMPs) selectively form pores in microbial membranes in process not fully understood. Here the authors use experimentally guided molecular dynamics to study maculatin pore formation, showing how this AMP assembles into transient and structurally diverse oligomeric pores in cel...

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Autores principales: Yukun Wang, Charles H. Chen, Dan Hu, Martin B. Ulmschneider, Jakob P. Ulmschneider
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/322f5d07a3e6460aa7ea543a7dc9effb
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