Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosidic linkages by use of remote participating groups.

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Autores principales: Heung Sik Hahm, Mattan Hurevich, Peter H Seeberger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/322fc83fe2004ff7aa51b9b5748470ab
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