Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosidic linkages by use of remote participating groups.

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Detalles Bibliográficos
Autores principales:	Heung Sik Hahm, Mattan Hurevich, Peter H Seeberger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/322fc83fe2004ff7aa51b9b5748470ab
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spelling	oai:doaj.org-article:322fc83fe2004ff7aa51b9b5748470ab2021-12-02T15:35:25ZAutomated assembly of oligosaccharides containing multiple cis-glycosidic linkages10.1038/ncomms124822041-1723https://doaj.org/article/322fc83fe2004ff7aa51b9b5748470ab2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12482https://doaj.org/toc/2041-1723Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosidic linkages by use of remote participating groups.Heung Sik HahmMattan HurevichPeter H SeebergerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Heung Sik Hahm Mattan Hurevich Peter H Seeberger Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
description	Automated glycan assembly has proven a powerful method to rapidly synthesize large oligosaccharides, though stereoselective cis-glycosylation remains a challenge. Here, the authors demonstrate a system to selectively incorporate multiple cis-glycosidic linkages by use of remote participating groups.
format	article
author	Heung Sik Hahm Mattan Hurevich Peter H Seeberger
author_facet	Heung Sik Hahm Mattan Hurevich Peter H Seeberger
author_sort	Heung Sik Hahm
title	Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
title_short	Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
title_full	Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
title_fullStr	Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
title_full_unstemmed	Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
title_sort	automated assembly of oligosaccharides containing multiple cis-glycosidic linkages
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/322fc83fe2004ff7aa51b9b5748470ab
work_keys_str_mv	AT heungsikhahm automatedassemblyofoligosaccharidescontainingmultiplecisglycosidiclinkages AT mattanhurevich automatedassemblyofoligosaccharidescontainingmultiplecisglycosidiclinkages AT peterhseeberger automatedassemblyofoligosaccharidescontainingmultiplecisglycosidiclinkages
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Automated assembly of oligosaccharides containing multiple cis-glycosidic linkages

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