The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, <i>Schistocerca gregaria</i>

The Effects of Structural Alterations in the Polyamine and Amino Acid Moieties of Philanthotoxins on Nicotinic Acetylcholine Receptor Inhibition in the Locust, <i>Schistocerca gregaria</i>

Alterations in the polyamine and amino acid (tyrosine) moieties of philanthotoxin-343 (PhTX-343) were investigated for their effects on the antagonism of nicotinic acetylcholine receptors (nAChRs) isolated from the locust (<i>Schistocerca gregaria</i>) mushroom body. Through whole-cell p...

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Auteurs principaux: Victoria L. Luck, David P. Richards, Ashif Y. Shaikh, Henrik Franzyk, Ian R. Mellor
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
philanthotoxin
nicotinic acetylcholine receptor
locust
neuron
patch-clamp
Organic chemistry
QD241-441
Accès en ligne:https://doaj.org/article/323019ba1285482aa81e01cc9063f5a9
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https://doaj.org/article/323019ba1285482aa81e01cc9063f5a9

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