Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion
ABSTRACT Extensive antigenic diversity within the GII.4 genotype of human norovirus is a major driver of pandemic emergence and a significant obstacle to development of cross-protective immunity after natural infection and vaccination. However, human and mouse monoclonal antibody studies indicate th...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/3234b0dad85f46aab63b050645be5abc |
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