Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution

Intermediate transitions between epithelial and mesenchymal states are associated with tumor progression. Here using mass cytometry, Plevritis and colleagues develop a computational framework to resolve and map these trajectories in lung cancer cells and clinical specimens.

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Autores principales: Loukia G. Karacosta, Benedict Anchang, Nikolaos Ignatiadis, Samuel C. Kimmey, Jalen A. Benson, Joseph B. Shrager, Robert Tibshirani, Sean C. Bendall, Sylvia K. Plevritis
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/32513de8c44b402d8bbb56fe5705714c
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