Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution

Hypoxia induced during inflammation promotes the resolution phase. Here the authors show that the hypoxia results from the respiratory burst in myeloid cells, and induces local EPO production and signaling, which enhances macrophage phagocytosis of debris and migration to draining lymph nodes to pro...

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Autores principales: Bangwei Luo, Jinsong Wang, Zongwei Liu, Zigang Shen, Rongchen Shi, Yu-Qi Liu, Yu Liu, Man Jiang, Yuzhang Wu, Zhiren Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/3257dde8948b486e9fead6e62f7fe079
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