Extreme Antibiotic Persistence via Heterogeneity-Generating Mutations Targeting Translation

ABSTRACT Antibiotic persistence, the noninherited tolerance of a subpopulation of bacteria to high levels of antibiotics, is a bet-hedging phenomenon with broad clinical implications. Indeed, the isolation of bacteria with substantially increased persistence rates from chronic infections suggests th...

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Auteurs principaux: Anupama Khare, Saeed Tavazoie
Format: article
Langue:EN
Publié: American Society for Microbiology 2020
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Accès en ligne:https://doaj.org/article/3259ae76ebf443869fd1673943ed5932
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