Molecular mechanism of cytoplasmic dynein tension sensing
The cytoplasmic motor protein dynein senses directional tension; its microtubule-binding domains bind microtubules more strongly when under backward load. Here the authors use optical tweezers to show that the linker, buttress, and stalk domains together regulate directional tension-sensing.
Enregistré dans:
| Auteurs principaux: | , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2019
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/325aff2c653c44afabe5feb61e8dc048 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|