Increased cardiovascular and renal risk is associated with low nephron endowment in aged females: an ovine model of fetal unilateral nephrectomy.

Previously we have shown that ovariectomised (OVX) female sheep have reduced renal function and elevated blood pressure from 6 months of age following fetal uninephrectomy (uni-x) at 100 days of gestation (term = 150 days). In the current study we examined if in intact female sheep the onset of decl...

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Autores principales: Reetu R Singh, Andrew J Jefferies, Yugeesh R Lankadeva, Paul Lombardo, Michal Schneider-Kolsky, Lucinda Hilliard, Kate M Denton, Karen M Moritz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/32692361cc614cc89402215525e17baa
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