Retinal Degeneration and Microglial Dynamics in Mature Progranulin-Deficient Mice

Progranulin (PGRN) is a secreted glycoprotein that regulates numerous cellular processes. The role of PGRN as a regulator of lysosomes has recently received attention. The purpose of this study was to characterize the retinal phenotype in mature PGRN knockout (<i>Grn</i><sup>−/−<...

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Autores principales: Kei Takahashi, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/3283d62f840a41fa85d9472b6f592bc0
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