Retinal Degeneration and Microglial Dynamics in Mature Progranulin-Deficient Mice
Progranulin (PGRN) is a secreted glycoprotein that regulates numerous cellular processes. The role of PGRN as a regulator of lysosomes has recently received attention. The purpose of this study was to characterize the retinal phenotype in mature PGRN knockout (<i>Grn</i><sup>−/−<...
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Autores principales: | Kei Takahashi, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/3283d62f840a41fa85d9472b6f592bc0 |
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