LY6E mediates an evolutionarily conserved enhancement of virus infection by targeting a late entry step

The interferon-induced gene LY6E increases virus infection, but the underlying mechanism is poorly understood. Here, Mar et al. show that LY6E enhances uncoating of influenza A virus after endosomal escape and that viral enhancement by LY6E is conserved across evolution.

Guardado en:
Detalles Bibliográficos
Autores principales: Katrina B. Mar, Nicholas R. Rinkenberger, Ian N. Boys, Jennifer L. Eitson, Matthew B. McDougal, R. Blake Richardson, John W. Schoggins
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/32b1f2d4d5494f82ad2fcf71b16e8791
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!