Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture

Abstract Three-dimensional models are considered a powerful tool for improving the concordance between in vitro and in vivo phenotypes. However, the duration of spheroid culture may influence the degree of correlation between these counterparts. When using immortalised cell lines as model systems, t...

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Autores principales: Andrea Antonio Ellero, Iman van den Bout, Maré Vlok, Allan Duncan Cromarty, Tracey Hurrell
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/32eca0f8407849fba20442dca1f15db0
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