Sensing and responding to allergic response cytokines through a genetically encoded circuit

The standard treatment for an allergic response is anti-histamines, steroids and anti-IgE antibodies. Here the authors present a genetic circuit that senses IL-4 and IL-13 and responses with DARPin production to bind IgE.

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Autores principales:	Hélène Chassin, Barbara Geering, Lina Schukur, David Ausländer, Brian Lang, Martin Fussenegger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/33084c3c97df4da3aeedbbb2271d4033
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spelling	oai:doaj.org-article:33084c3c97df4da3aeedbbb2271d40332021-12-02T15:38:37ZSensing and responding to allergic response cytokines through a genetically encoded circuit10.1038/s41467-017-01211-12041-1723https://doaj.org/article/33084c3c97df4da3aeedbbb2271d40332017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01211-1https://doaj.org/toc/2041-1723The standard treatment for an allergic response is anti-histamines, steroids and anti-IgE antibodies. Here the authors present a genetic circuit that senses IL-4 and IL-13 and responses with DARPin production to bind IgE.Hélène ChassinBarbara GeeringLina SchukurDavid AusländerBrian LangMartin FusseneggerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hélène Chassin Barbara Geering Lina Schukur David Ausländer Brian Lang Martin Fussenegger Sensing and responding to allergic response cytokines through a genetically encoded circuit
description	The standard treatment for an allergic response is anti-histamines, steroids and anti-IgE antibodies. Here the authors present a genetic circuit that senses IL-4 and IL-13 and responses with DARPin production to bind IgE.
format	article
author	Hélène Chassin Barbara Geering Lina Schukur David Ausländer Brian Lang Martin Fussenegger
author_facet	Hélène Chassin Barbara Geering Lina Schukur David Ausländer Brian Lang Martin Fussenegger
author_sort	Hélène Chassin
title	Sensing and responding to allergic response cytokines through a genetically encoded circuit
title_short	Sensing and responding to allergic response cytokines through a genetically encoded circuit
title_full	Sensing and responding to allergic response cytokines through a genetically encoded circuit
title_fullStr	Sensing and responding to allergic response cytokines through a genetically encoded circuit
title_full_unstemmed	Sensing and responding to allergic response cytokines through a genetically encoded circuit
title_sort	sensing and responding to allergic response cytokines through a genetically encoded circuit
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/33084c3c97df4da3aeedbbb2271d4033
work_keys_str_mv	AT helenechassin sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit AT barbarageering sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit AT linaschukur sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit AT davidauslander sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit AT brianlang sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit AT martinfussenegger sensingandrespondingtoallergicresponsecytokinesthroughageneticallyencodedcircuit
_version_	1718386102910320640

Sensing and responding to allergic response cytokines through a genetically encoded circuit

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