LTA4H rs2660845 association with montelukast response in early and late-onset asthma.

LTA4H rs2660845 association with montelukast response in early and late-onset asthma.

Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the role of the LTA4H regulatory variant rs2660845 and age of asthma onset in response to montelukast in ethnic...

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Détails bibliographiques
Auteurs principaux: Cyrielle Maroteau, Antonio Espuela-Ortiz, Esther Herrera-Luis, Sundararajan Srinivasan, Fiona Carr, Roger Tavendale, Karen Wilson, Natalia Hernandez-Pacheco, James D Chalmers, Steve Turner, Somnath Mukhopadhyay, Anke-Hilse Maitland-van der Zee, Esteban G Burchard, Maria Pino-Yanes, Simon Young, Glenda Lassi, Adam Platt, Colin N A Palmer, PiCA Consortium
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/336ae4e495164e158dd79d9dc9b0ed2d
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Internet

https://doaj.org/article/336ae4e495164e158dd79d9dc9b0ed2d

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