The next generation of transcription factor binding site prediction.

Finding where transcription factors (TFs) bind to the DNA is of key importance to decipher gene regulation at a transcriptional level. Classically, computational prediction of TF binding sites (TFBSs) is based on basic position weight matrices (PWMs) which quantitatively score binding motifs based o...

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Bibliographic Details
Main Authors: Anthony Mathelier, Wyeth W Wasserman
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Online Access:https://doaj.org/article/338acd7d9de14561884e55355d54b698
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