A novel CpG island set identifies tissue-specific methylation at developmental gene loci.
CpG islands (CGIs) are dense clusters of CpG sequences that punctuate the CpG-deficient human genome and associate with many gene promoters. As CGIs also differ from bulk chromosomal DNA by their frequent lack of cytosine methylation, we devised a CGI enrichment method based on nonmethylated CpG aff...
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Auteurs principaux: | , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2008
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Accès en ligne: | https://doaj.org/article/33b0f73ece2d4373b071dcf909a6f631 |
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