IgD attenuates the IgM-induced anergy response in transitional and mature B cells
Self-reactive B cells that are anergic express mainly IgD, yet the function of IgD is not clear. Here the authors analyse primary B cells from mice to show that IgD signalling attenuates self-antigen induced gene expression and promotes survival of anergic B cells that might go on to reactivate to f...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2016
|
| Subjects: | |
| Online Access: | https://doaj.org/article/33bf5d14b2104b7e9e5694830f9f9ee0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|