A collagen glucosyltransferase drives lung adenocarcinoma progression in mice

Guo et al. determine the molecular basis of collagen lysyl hydroxylase 2 (LH2) substrate specificity. They further show that LH2 also functions as a collagen glucosyltransferase to promote lung cancer progression.

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Autores principales:	Hou-Fu Guo, Neus Bota-Rabassedas, Masahiko Terajima, B. Leticia Rodriguez, Don L. Gibbons, Yulong Chen, Priyam Banerjee, Chi-Lin Tsai, Xiaochao Tan, Xin Liu, Jiang Yu, Michal Tokmina-Roszyk, Roma Stawikowska, Gregg B. Fields, Mitchell D. Miller, Xiaoyan Wang, Juhoon Lee, Kevin N. Dalby, Chad J. Creighton, George N. Phillips, John A. Tainer, Mitsuo Yamauchi, Jonathan M. Kurie
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/33c609a5058f4848b50950a0e6133563
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spelling	oai:doaj.org-article:33c609a5058f4848b50950a0e61335632021-12-02T18:28:59ZA collagen glucosyltransferase drives lung adenocarcinoma progression in mice10.1038/s42003-021-01982-w2399-3642https://doaj.org/article/33c609a5058f4848b50950a0e61335632021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01982-whttps://doaj.org/toc/2399-3642Guo et al. determine the molecular basis of collagen lysyl hydroxylase 2 (LH2) substrate specificity. They further show that LH2 also functions as a collagen glucosyltransferase to promote lung cancer progression.Hou-Fu GuoNeus Bota-RabassedasMasahiko TerajimaB. Leticia RodriguezDon L. GibbonsYulong ChenPriyam BanerjeeChi-Lin TsaiXiaochao TanXin LiuJiang YuMichal Tokmina-RoszykRoma StawikowskaGregg B. FieldsMitchell D. MillerXiaoyan WangJuhoon LeeKevin N. DalbyChad J. CreightonGeorge N. PhillipsJohn A. TainerMitsuo YamauchiJonathan M. KurieNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Hou-Fu Guo Neus Bota-Rabassedas Masahiko Terajima B. Leticia Rodriguez Don L. Gibbons Yulong Chen Priyam Banerjee Chi-Lin Tsai Xiaochao Tan Xin Liu Jiang Yu Michal Tokmina-Roszyk Roma Stawikowska Gregg B. Fields Mitchell D. Miller Xiaoyan Wang Juhoon Lee Kevin N. Dalby Chad J. Creighton George N. Phillips John A. Tainer Mitsuo Yamauchi Jonathan M. Kurie A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
description	Guo et al. determine the molecular basis of collagen lysyl hydroxylase 2 (LH2) substrate specificity. They further show that LH2 also functions as a collagen glucosyltransferase to promote lung cancer progression.
format	article
author	Hou-Fu Guo Neus Bota-Rabassedas Masahiko Terajima B. Leticia Rodriguez Don L. Gibbons Yulong Chen Priyam Banerjee Chi-Lin Tsai Xiaochao Tan Xin Liu Jiang Yu Michal Tokmina-Roszyk Roma Stawikowska Gregg B. Fields Mitchell D. Miller Xiaoyan Wang Juhoon Lee Kevin N. Dalby Chad J. Creighton George N. Phillips John A. Tainer Mitsuo Yamauchi Jonathan M. Kurie
author_facet	Hou-Fu Guo Neus Bota-Rabassedas Masahiko Terajima B. Leticia Rodriguez Don L. Gibbons Yulong Chen Priyam Banerjee Chi-Lin Tsai Xiaochao Tan Xin Liu Jiang Yu Michal Tokmina-Roszyk Roma Stawikowska Gregg B. Fields Mitchell D. Miller Xiaoyan Wang Juhoon Lee Kevin N. Dalby Chad J. Creighton George N. Phillips John A. Tainer Mitsuo Yamauchi Jonathan M. Kurie
author_sort	Hou-Fu Guo
title	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
title_short	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
title_full	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
title_fullStr	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
title_full_unstemmed	A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
title_sort	collagen glucosyltransferase drives lung adenocarcinoma progression in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/33c609a5058f4848b50950a0e6133563
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A collagen glucosyltransferase drives lung adenocarcinoma progression in mice

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