Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin

Abstract Most patients with hepatocellular carcinoma (HCC) are in the middle or advanced stage at the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to verify whether deoxythymidylate kinase (DTYMK) increased in HCC and was an effective therapeutic target in HC...

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Auteurs principaux: Fengze Sun, Yuanyuan Liu, Tingting Gong, Qiuzhong Pan, Tong Xiang, Jingjing Zhao, Yan Tang, Hao Chen, Yulong Han, Mengjia Song, Yue Huang, Han Li, Yuanyuan Chen, Chaopin Yang, Jieying Yang, Qijing Wang, Yongqiang Li, Jia He, Desheng Weng, Ruiqing Peng, Jianchuan Xia
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/33d3a7e398e24d5bbbe7ee462a878d6f
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