DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14<sup>+</sup> CD16<sup>+</sup> CD64<sup>high</sup> CD32<sup>low</sup> Inflammatory Monocytes from Malaria Patients

DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14<sup>+</sup> CD16<sup>+</sup> CD64<sup>high</sup> CD32<sup>low</sup> Inflammatory Monocytes from Malaria Patients

ABSTRACT High levels of circulating immunocomplexes (ICs) are found in patients with either infectious or sterile inflammation. We report that patients with either Plasmodium falciparum or Plasmodium vivax malaria have increased levels of circulating anti-DNA antibodies and ICs containing parasite D...

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Autores principales: Isabella C. Hirako, Carolina Gallego-Marin, Marco A. Ataide, Warrison A. Andrade, Humberto Gravina, Bruno C. Rocha, Rosane B. de Oliveira, Dhelio B. Pereira, Joseph Vinetz, Betty Diamond, Sanjay Ram, Douglas T. Golenbock, Ricardo T. Gazzinelli
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/33ef047a24c34bcc87c54300905ab770
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https://doaj.org/article/33ef047a24c34bcc87c54300905ab770

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