Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation
ABSTRACT The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication. CCC DNA is converted from a relaxed circular (RC) DNA, in which nei...
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Main Authors: | , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2020
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Subjects: | |
Online Access: | https://doaj.org/article/342fda5c28d14647b4492bc2800ff555 |
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