Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation

ABSTRACT The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication. CCC DNA is converted from a relaxed circular (RC) DNA, in which nei...

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Bibliographic Details
Main Authors: Jun Luo, Laurie Luckenbaugh, Hui Hu, Zhipeng Yan, Lu Gao, Jianming Hu
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
ATR
Online Access:https://doaj.org/article/342fda5c28d14647b4492bc2800ff555
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