Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation
ABSTRACT The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication. CCC DNA is converted from a relaxed circular (RC) DNA, in which nei...
Guardado en:
Autores principales: | Jun Luo, Laurie Luckenbaugh, Hui Hu, Zhipeng Yan, Lu Gao, Jianming Hu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Acceso en línea: | https://doaj.org/article/342fda5c28d14647b4492bc2800ff555 |
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