Is the Nickel-Dependent Urease Complex of <italic toggle="yes">Cryptococcus</italic> the Pathogen’s Achilles’ Heel?

ABSTRACT The nitrogen-scavenging enzyme urease has been coopted in a variety of pathogenic organisms as a virulence factor, most notoriously to neutralize stomach acid and establish infection by the gastric pathogen Helicobacter pylori. The opportunistic fungal pathogen Cryptococcus neoformans also...

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Bibliographic Details
Main Authors: Carl A. Morrow, James A. Fraser
Format: article
Language:EN
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://doaj.org/article/34304ef016c94cfbbbfb1d03393065fd
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