The Combination of Rifampin plus Moxifloxacin Is Synergistic for Suppression of Resistance but Antagonistic for Cell Kill of <italic toggle="yes">Mycobacterium tuberculosis</italic> as Determined in a Hollow-Fiber Infection Model
ABSTRACT Moxifloxacin is under development for expanded use against Mycobacterium tuberculosis. Rifampin is a mainstay of therapy. We examined the interaction of moxifloxacin plus rifampin for log-phase and nonreplicating persister (NRP) organisms. For this evaluation, we employed our hollow-fiber i...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2010
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Acceso en línea: | https://doaj.org/article/346a155c92eb441da601c67a03e408da |
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