A Molecular Basis for Selective Antagonist Destabilization of Dopamine D3 Receptor Quaternary Organization

Abstract The dopamine D3 receptor (D3R) is a molecular target for both first-generation and several recently-developed antipsychotic agents. Following stable expression of this mEGFP-tagged receptor, Spatial Intensity Distribution Analysis indicated that a substantial proportion of the receptor was...

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Autores principales: Sara Marsango, Gianluigi Caltabiano, Mireia Jiménez-Rosés, Mark J. Millan, John D. Pediani, Richard J. Ward, Graeme Milligan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/3470a476fb0447e9a1e204628cce051b
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