Development of a human umbilical cord-derived mesenchymal stromal cell-based advanced therapy medicinal product to treat immune and/or inflammatory diseases

Development of a human umbilical cord-derived mesenchymal stromal cell-based advanced therapy medicinal product to treat immune and/or inflammatory diseases

Abstract Background Umbilical cord-derived mesenchymal stromal cells (UC-MSCs) revealed their key role in immune regulation, offering promising therapeutic perspectives for immune and inflammatory diseases. We aimed to develop a production process of an UC-MSC-based product and then to characterize...

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Autores principales: Miryam Mebarki, Nathan Iglicki, Céline Marigny, Camille Abadie, Claire Nicolet, Guillaume Churlaud, Camille Maheux, Hélène Boucher, Antoine Monsel, Philippe Menasché, Jérôme Larghero, Lionel Faivre, Audrey Cras
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Human umbilical cord
Mesenchymal stromal cells
Immunomodulation
Inflammation
Advanced therapy medicinal product
Good manufacturing practice
Medicine (General)
R5-920
Biochemistry
QD415-436
Acceso en línea:https://doaj.org/article/347d91d1927840198e1681f77e14c9f8
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https://doaj.org/article/347d91d1927840198e1681f77e14c9f8

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