Extreme genetic fragility of the HIV-1 capsid.

Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be particularly advantageous to them. The capsid (CA) do...

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Autores principales: Suzannah J Rihn, Sam J Wilson, Nick J Loman, Mudathir Alim, Saskia E Bakker, David Bhella, Robert J Gifford, Frazer J Rixon, Paul D Bieniasz
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/34a40bd4ec5d4f0b983759833986b91d
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