Long-Term Depression of Striatal DA Release Induced by mGluRs via Sustained Hyperactivity of Local Cholinergic Interneurons

The cellular mechanisms regulating dopamine (DA) release in the striatum have attracted much interest in recent years. By in vitro amperometric recordings in mouse striatal slices, we show that a brief (5 min) exposure to the metabotropic glutamate receptor agonist DHPG (50 μM) induces a profound de...

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Autores principales: Nicola B. Mercuri, Mauro Federici, Francesca Romana Rizzo, Lorenzo Maugeri, Sebastian L. D’Addario, Rossella Ventura, Nicola Berretta
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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LTD
Acceso en línea:https://doaj.org/article/34bbf5a0412348b482487d602f9dba65
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