A mechanism for the polarity formation of chemoreceptors at the growth cone membrane for gradient amplification during directional sensing.

Accurate response to external directional signals is essential for many physiological functions such as chemotaxis or axonal guidance. It relies on the detection and amplification of gradients of chemical cues, which, in eukaryotic cells, involves the asymmetric relocalization of signaling molecules...

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Auteurs principaux: Cedric Bouzigues, David Holcman, Maxime Dahan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2010
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R
Q
Accès en ligne:https://doaj.org/article/34c1c5f3b8a4485b9106956264772afc
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