A mechanism for the polarity formation of chemoreceptors at the growth cone membrane for gradient amplification during directional sensing.

Accurate response to external directional signals is essential for many physiological functions such as chemotaxis or axonal guidance. It relies on the detection and amplification of gradients of chemical cues, which, in eukaryotic cells, involves the asymmetric relocalization of signaling molecules...

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Autores principales: Cedric Bouzigues, David Holcman, Maxime Dahan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/34c1c5f3b8a4485b9106956264772afc
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