Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase

Human manganese superoxide dismutase (MnSOD) is an oxidoreductase that uses concerted proton and electron transfers to reduce the levels of superoxide radicals in mitochondria, but mechanistic insights into this process are limited. Here, the authors report neutron crystal structures of Mn3+SOD and...

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Autores principales: Jahaun Azadmanesh, William E. Lutz, Leighton Coates, Kevin L. Weiss, Gloria E. O. Borgstahl
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/34eb2c72ba2b44c2b7fd4909831c5a50
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