Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase
Human manganese superoxide dismutase (MnSOD) is an oxidoreductase that uses concerted proton and electron transfers to reduce the levels of superoxide radicals in mitochondria, but mechanistic insights into this process are limited. Here, the authors report neutron crystal structures of Mn3+SOD and...
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Auteurs principaux: | Jahaun Azadmanesh, William E. Lutz, Leighton Coates, Kevin L. Weiss, Gloria E. O. Borgstahl |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
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Accès en ligne: | https://doaj.org/article/34eb2c72ba2b44c2b7fd4909831c5a50 |
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