Targeted Knockout of the <named-content content-type="genus-species">Rickettsia rickettsii</named-content> OmpA Surface Antigen Does Not Diminish Virulence in a Mammalian Model System
ABSTRACT Strains of Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever (RMSF), differ dramatically in virulence despite >99% genetic homology. Spotted fever group (SFG) rickettsiae produce two immunodominant outer membrane proteins, rickettsial OmpA (rOmpA) and rOmpB, whic...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2015
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/350a310c223c41e8963c69942a4305a3 |
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