Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans

Diez et al. show that glycolate suppresses deleterious effects of peroxide on mitochondrial activity and growth of worms. They find that the conversion of glycolate into glycine and serine helps worms maintain cellular antioxidants following oxidative stress. This study suggests that glycolate serve...

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Auteurs principaux: Veronica Diez, Sofia Traikov, Kathrin Schmeisser, Akshay Kumar Das Adhikari, Teymuras Vakhtang Kurzchalia
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/351400b9b8fe47429efa1cb3ef038151
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