Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans

Diez et al. show that glycolate suppresses deleterious effects of peroxide on mitochondrial activity and growth of worms. They find that the conversion of glycolate into glycine and serine helps worms maintain cellular antioxidants following oxidative stress. This study suggests that glycolate serve...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Veronica Diez, Sofia Traikov, Kathrin Schmeisser, Akshay Kumar Das Adhikari, Teymuras Vakhtang Kurzchalia
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/351400b9b8fe47429efa1cb3ef038151
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:351400b9b8fe47429efa1cb3ef038151
record_format	dspace
spelling	oai:doaj.org-article:351400b9b8fe47429efa1cb3ef0381512021-12-02T10:44:14ZGlycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans10.1038/s42003-021-01669-22399-3642https://doaj.org/article/351400b9b8fe47429efa1cb3ef0381512021-02-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01669-2https://doaj.org/toc/2399-3642Diez et al. show that glycolate suppresses deleterious effects of peroxide on mitochondrial activity and growth of worms. They find that the conversion of glycolate into glycine and serine helps worms maintain cellular antioxidants following oxidative stress. This study suggests that glycolate serves as a natural antioxidant improving organismal fitness under stress.Veronica DiezSofia TraikovKathrin SchmeisserAkshay Kumar Das AdhikariTeymuras Vakhtang KurzchaliaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Veronica Diez Sofia Traikov Kathrin Schmeisser Akshay Kumar Das Adhikari Teymuras Vakhtang Kurzchalia Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
description	Diez et al. show that glycolate suppresses deleterious effects of peroxide on mitochondrial activity and growth of worms. They find that the conversion of glycolate into glycine and serine helps worms maintain cellular antioxidants following oxidative stress. This study suggests that glycolate serves as a natural antioxidant improving organismal fitness under stress.
format	article
author	Veronica Diez Sofia Traikov Kathrin Schmeisser Akshay Kumar Das Adhikari Teymuras Vakhtang Kurzchalia
author_facet	Veronica Diez Sofia Traikov Kathrin Schmeisser Akshay Kumar Das Adhikari Teymuras Vakhtang Kurzchalia
author_sort	Veronica Diez
title	Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
title_short	Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
title_full	Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
title_fullStr	Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
title_full_unstemmed	Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans
title_sort	glycolate combats massive oxidative stress by restoring redox potential in caenorhabditis elegans
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/351400b9b8fe47429efa1cb3ef038151
work_keys_str_mv	AT veronicadiez glycolatecombatsmassiveoxidativestressbyrestoringredoxpotentialincaenorhabditiselegans AT sofiatraikov glycolatecombatsmassiveoxidativestressbyrestoringredoxpotentialincaenorhabditiselegans AT kathrinschmeisser glycolatecombatsmassiveoxidativestressbyrestoringredoxpotentialincaenorhabditiselegans AT akshaykumardasadhikari glycolatecombatsmassiveoxidativestressbyrestoringredoxpotentialincaenorhabditiselegans AT teymurasvakhtangkurzchalia glycolatecombatsmassiveoxidativestressbyrestoringredoxpotentialincaenorhabditiselegans
_version_	1718396757275049984

Glycolate combats massive oxidative stress by restoring redox potential in Caenorhabditis elegans

Ejemplares similares