<italic toggle="yes">De Novo</italic> Pyrimidine Biosynthesis Connects Cell Integrity to Amphotericin B Susceptibility in <named-content content-type="genus-species">Cryptococcus neoformans</named-content>
ABSTRACT The use of amphotericin B (AmB) in conjunction with 5-fluorocytosine (5-FC) is known to be the optimal therapy for treating cryptococcosis, but the mechanism by which 5-FC synergizes with AmB is unknown. In this study, we generated a Cryptococcus neoformansura1Δ mutant lacking dihydroorotat...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2016
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/352b6dce94c0481fbdab1987d07eb3a2 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|