Altered ureteric branching morphogenesis and nephron endowment in offspring of diabetic and insulin-treated pregnancy.

There is strong evidence from human and animal models that exposure to maternal hyperglycemia during in utero development can detrimentally affect fetal kidney development. Notwithstanding this knowledge, the precise effects of diabetic pregnancy on the key processes of kidney development are unclea...

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Autores principales: Stacey N Hokke, James A Armitage, Victor G Puelles, Kieran M Short, Lynelle Jones, Ian M Smyth, John F Bertram, Luise A Cullen-McEwen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/354f71efdc2e42c79410921dbb514e3b
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