Dysregulation of Cytoskeleton Remodeling Drives Invasive Leading Cells Detachment

Detachment of cancer cells is the first step in tumor metastasis and malignancy. However, studies on the balance of initial tumor anchoring and detachment are limited. Herein, we revealed that the regulation of cytoskeleton proteins potentiates tumor detachment. The blockage of TGF-β1 using neutrali...

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Auteurs principaux: Jei-Ming Peng, Wei-Yu Chen, Jai-Hong Cheng, Jia-Wun Luo, Hong-Tai Tzeng
Format: article
Langue:EN
Publié: MDPI AG 2021
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Accès en ligne:https://doaj.org/article/355202647d7743a9885614105910abc5
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