Worm proteins of Schistosoma mansoni reduce the severity of experimental chronic colitis in mice by suppressing colonic proinflammatory immune responses.

Although helminthic therapy as a possible new option to treat inflammatory bowel disease is a well-established concept by now, the search for immunomodulatory helminth-derived compounds and their mechanisms of action is still ongoing. We investigated the therapeutic potential and the underlying immu...

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Auteurs principaux: Marthe Heylen, Nathalie E Ruyssers, Joris G De Man, Jean-Pierre Timmermans, Paul A Pelckmans, Tom G Moreels, Benedicte Y De Winter
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
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Accès en ligne:https://doaj.org/article/3555ba539bee4192ad297b97cc75fc31
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