Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype.

During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growth p...

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Autores principales: Johan Kerkhofs, Scott J Roberts, Frank P Luyten, Hans Van Oosterwyck, Liesbet Geris
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/3587aac68a6c42ef9fc3ed50a70e8600
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