Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype.
During endochondral ossification, chondrocyte growth and differentiation is controlled by many local signalling pathways. Due to crosstalks and feedback mechanisms, these interwoven pathways display a network like structure. In this study, a large-scale literature based logical model of the growth p...
Guardado en:
Autores principales: | Johan Kerkhofs, Scott J Roberts, Frank P Luyten, Hans Van Oosterwyck, Liesbet Geris |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/3587aac68a6c42ef9fc3ed50a70e8600 |
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