Tracking of Antibiotic Resistance Transfer and Rapid Plasmid Evolution in a Hospital Setting by Nanopore Sequencing

Tracking of Antibiotic Resistance Transfer and Rapid Plasmid Evolution in a Hospital Setting by Nanopore Sequencing

ABSTRACT Infections with multidrug-resistant bacteria often leave limited or no treatment options. The transfer of antimicrobial resistance genes (ARG) carrying plasmids between bacterial species by horizontal gene transfer represents an important mode of expansion of ARGs. Here, we demonstrate the...

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Autores principales: Silke Peter, Mattia Bosio, Caspar Gross, Daniela Bezdan, Javier Gutierrez, Philipp Oberhettinger, Jan Liese, Wichard Vogel, Daniela Dörfel, Lennard Berger, Matthias Marschal, Matthias Willmann, Ivo Gut, Marta Gut, Ingo Autenrieth, Stephan Ossowski
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
plasmids
Nanopore
long read
IMP-8
Pseudomonas aeruginosa
pathoLogic
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/35b1d28e71cc428eb732c4f78e2caa9f
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https://doaj.org/article/35b1d28e71cc428eb732c4f78e2caa9f

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