Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are recruited to wound edges in cells and are requi...

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Autores principales: Theresa Louise Boye, Kenji Maeda, Weria Pezeshkian, Stine Lauritzen Sønder, Swantje Christin Haeger, Volker Gerke, Adam Cohen Simonsen, Jesper Nylandsted
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/35ba979e75e6437e87c4c03e0402bae3
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