Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are recruited to wound edges in cells and are requi...

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Autores principales:	Theresa Louise Boye, Kenji Maeda, Weria Pezeshkian, Stine Lauritzen Sønder, Swantje Christin Haeger, Volker Gerke, Adam Cohen Simonsen, Jesper Nylandsted
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/35ba979e75e6437e87c4c03e0402bae3
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spelling	oai:doaj.org-article:35ba979e75e6437e87c4c03e0402bae32021-12-02T14:40:48ZAnnexin A4 and A6 induce membrane curvature and constriction during cell membrane repair10.1038/s41467-017-01743-62041-1723https://doaj.org/article/35ba979e75e6437e87c4c03e0402bae32017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01743-6https://doaj.org/toc/2041-1723The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are recruited to wound edges in cells and are required for repair.Theresa Louise BoyeKenji MaedaWeria PezeshkianStine Lauritzen SønderSwantje Christin HaegerVolker GerkeAdam Cohen SimonsenJesper NylandstedNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Theresa Louise Boye Kenji Maeda Weria Pezeshkian Stine Lauritzen Sønder Swantje Christin Haeger Volker Gerke Adam Cohen Simonsen Jesper Nylandsted Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
description	The role of annexins in cell membrane repair is largely undefined. Here the authors use a model lipid bilayer to show that annexin A4 induces curvature at the membrane free edge and annexin A6 induces constriction force, and find that both annexins are recruited to wound edges in cells and are required for repair.
format	article
author	Theresa Louise Boye Kenji Maeda Weria Pezeshkian Stine Lauritzen Sønder Swantje Christin Haeger Volker Gerke Adam Cohen Simonsen Jesper Nylandsted
author_facet	Theresa Louise Boye Kenji Maeda Weria Pezeshkian Stine Lauritzen Sønder Swantje Christin Haeger Volker Gerke Adam Cohen Simonsen Jesper Nylandsted
author_sort	Theresa Louise Boye
title	Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
title_short	Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
title_full	Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
title_fullStr	Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
title_full_unstemmed	Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
title_sort	annexin a4 and a6 induce membrane curvature and constriction during cell membrane repair
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/35ba979e75e6437e87c4c03e0402bae3
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Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

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