Identification of significantly mutated subnetworks in the breast cancer genome
Abstract Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this r...
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Main Authors: | Rasif Ajwad, Michael Domaratzki, Qian Liu, Nikta Feizi, Pingzhao Hu |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/35eb7bde4a5b4476838f5f4ffa421d0f |
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