Protein structure shapes immunodominance in the CD4 T cell response to yellow fever vaccination
Abstract The live attenuated yellow fever (YF) vaccine is a highly effective human vaccine and induces long-term protective neutralizing antibodies directed against the viral envelope protein E. The generation of such antibodies requires the help of CD4 T cells which recognize peptides derived from...
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Main Authors: | Maximilian Koblischke, Maria S. Mackroth, Julia Schwaiger, Ingrid Fae, Gottfried Fischer, Karin Stiasny, Franz X. Heinz, Judith H. Aberle |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/35ef5b775d3f48c6aac68f1e1dfc2a8b |
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