Time-resolved non-invasive metabolomic monitoring of a single cancer spheroid by microfluidic NMR

Abstract We present a quantitative study of the metabolic activity of a single spheroid culture of human cancer cells. NMR (nuclear magnetic resonance) spectroscopy is an ideal tool for observation of live systems due to its non-invasive nature. However, limited sensitivity has so far hindered its a...

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Bibliographic Details
Main Authors: Bishnubrata Patra, Manvendra Sharma, William Hale, Marcel Utz
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/36803785c8414c4f97f0b765608eed58
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